ANTISYNTHETASE SYNDROME-RELATED ILD - DIAGNOSIS
DIAGNOSIS
| FOR ANTISYTHETASE SYNDROME1 | FOR ANTISYTHETASE SYNDROME-RELATED ILD1,6 | ||
|---|---|---|---|
| Established diagnosis of antisynthetase syndrome OR comprehensive medical history + physical exam + serologies (anti-aminoacyl tRNA synthetase (anti-ARS); anti-Jo1) + muscle biopsy |
PFTs | HRCT | Lung Biopsy |
| Restrictive defect | Nonspecific interstitial pneumonia (NSIP) Organizing pneumonia (OP) Most common signs: Traction bronchiectasis, ground glass, reticulation |
Not always necessary | |
