SYSTEMIC SCLEROSIS-RELATED ILD - DIAGNOSIS
DIAGNOSIS7
Symptoms
- Calcinosis
- Raynaud’s phenomenon
- Articular involvement
- Esophageal dysmotility
- Lung fibrosis
- Isolated pulmonary arterial hypertension
- Heart involvement
- Renal crisis
SSc-ILD: Diagnosis
| FOR SSc3,7,8,13 | FOR SSc-ILD8,14-17 | ||
|---|---|---|---|
| Established diagnosis of SSc OR Clinical history + physical exam + serologies (e.g., anti-Scl-70; anti-U3RNP, anti-Th/To) |
PFTs | HRCT | Lung Biopsy |
| Restrictive defect (or mixed, if other comorbidities present) | NSIP UIP also seen but rarer |
NSIP (mostly) Lung biopsy not commonly performed |
|
