SYSTEMIC SCLEROSIS-RELATED ILD - DIAGNOSIS

DIAGNOSIS7

Symptoms

  • Calcinosis
  • Raynaud’s phenomenon
  • Articular involvement
  • Esophageal dysmotility
  • Lung fibrosis
  • Isolated pulmonary arterial hypertension
  • Heart involvement
  • Renal crisis

SSc-ILD: Diagnosis

FOR SSc3,7,8,13 FOR SSc-ILD8,14-17
Established diagnosis of SSc
OR
Clinical history + physical exam + serologies (e.g., anti-Scl-70; anti-U3RNP, anti-Th/To)
PFTs HRCT Lung Biopsy
Restrictive defect (or mixed, if other comorbidities present) NSIP
  UIP also seen but rarer
NSIP (mostly)
Lung biopsy not commonly performed

See also

Patient Case Study 1

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Interstitial lung disease in systemic sclerosis with a focus on chest CT

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