IPF has a lower 5-year survival rate compared with many common cancers1,2*

5-year survival rate in IPF vs types of cancer chart 5-year survival rate in IPF vs types of cancer chart

*The 5-year survival rate for IPF was based on a systematic review and meta-analysis including 14 studies (both US and ex-US) published after 2010.1 5-year relative survival rates for cancer sites are based on cases diagnosed from 2013 to 2019.2

†Excludes appendiceal cancers.2

Pulmonary fibrosis can become progressive in ILDs other than IPF and is associated with a poor prognosis3

IPF is the prototypical fibrosing ILD with a progressive phenotype, but other ILDs also are at risk of developing progressive pulmonary fibrosis. ILDs with progressive pulmonary fibrosis behave in a clinically similar way to IPF and are characterized by:

Progressive pulmonary fibrosis is characterized by:

Graphic showing lung function decline

Lung function
decline

Graphic showing worsening respiratory symptoms

Worsening respiratory
symptoms

Graphic showing worsening quality of life

Worsening
quality of life

Graphic showing early mortality

Early
mortality

IPF is an ILD that is always progressive4

Presenting symptoms of ILD are nonspecific graphic Presenting symptoms of ILD are nonspecific graphic Recognize signs of ILD 
Testing for ILDs graphic Testing for ILDs graphic Learn about reviewing tests and scans 
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ILD, interstitial lung disease; IPF, idiopathic pulmonary fibrosis.

References

  1. Zheng Q et al. ERJ Open Res. 2022;8(1):00591-2021.
  2. Siegel RL et al. CA Cancer J Clin. 2024;74(1):12-49.
  3. Cottin V et al. Eur Respir Rev. 2018;27(150):180076.
  4. Raghu G et al. Am J Respir Crit Care Med. 2011;183(6):788-824.
  5. Zibrak JD, Price D. NPJ Prim Care Respir Med. 2014;24:14054.